pentobarbital will decrease the level or effect of ripretinib ort affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will decrease the level or effect of fosamprenavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Skärm.pentobarbital will decrease the level or effect of lumacaftor/ivacaftor samhälle affect